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Allisartan Isoproxil
CAS No. 947331-05-7
Allisartan Isoproxil ( —— )
产品货号. M27845 CAS No. 947331-05-7
Allisartan Isoproxil 是一种血管紧张素 II 受体拮抗剂，用于治疗轻度至中度原发性高血压。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥2373 | 有现货 |
|
| 5MG | ￥3629 | 有现货 |
|
| 10MG | ￥5330 | 有现货 |
|
| 25MG | ￥7995 | 有现货 |
|
| 50MG | ￥11178 | 有现货 |
|
| 100MG | ￥15309 | 有现货 |
|
| 500MG | ￥30618 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Allisartan Isoproxil
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Allisartan Isoproxil 是一种血管紧张素 II 受体拮抗剂，用于治疗轻度至中度原发性高血压。
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产品描述Allisartan Isoproxil, an angiotensin II receptor antagonist, is used to treat mild to moderate essential hypertension.
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体外实验——
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体内实验Animal Model:Femal and male Sprague-Dawley ratsDosage:20, 80 and 320 mg/kg Administration:Result:Decreased body-weight gain at 320 mg/kg/day in both sexes as well as at the 80-mg/kg/day dose in females. Decreased erythrocyte parameters in males, and decreased heart weight and exacerbation of chronic progressive nephropathy (CPN) severity in males at 80 and 320 mg/kg/day.
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同义词——
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通路Others
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靶点Other Targets
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受体Furin
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研究领域——
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适应症——
化学信息
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CAS Number947331-05-7
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分子量553.02
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分子式C27H29ClN6O5
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO : 100 mg/mL (180.83 mM)
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SMILESCCCCc1nc(Cl)c(C(=O)OCOC(=O)OC(C)C)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Lisa E J Douglas, et al. A highly selective, cell-permeable furin inhibitor BOS-318 rescues key features of cystic fibrosis airway disease. Cell Chem Biol. 2022 Jun 16;29(6):947-957.e8.
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